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Ludo A M Broos Selected Research

voltage-dependent calcium channel (P-Q type)

1/2017Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine.
3/2014RNA expression profiling in brains of familial hemiplegic migraine type 1 knock-in mice.
9/2010Severe and progressive neurotransmitter release aberrations in familial hemiplegic migraine type 1 Cacna1a S218L knock-in mice.
7/2010Quantitative cortical synapse proteomics of a transgenic migraine mouse model with mutated Ca(V)2.1 calcium channels.
1/2010High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice.
12/2006Conditional inactivation of the Cacna1a gene in transgenic mice.
12/2004Familial hemiplegic migraine type 1 mutations K1336E, W1684R, and V1696I alter Cav2.1 Ca2+ channel gating: evidence for beta-subunit isoform-specific effects.
3/2004A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression.

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Ludo A M Broos Research Topics

Disease

7Migraine with Aura (Familial Hemiplegic Migraine)
01/2017 - 03/2004
4Migraine Disorders (Migraine)
03/2014 - 03/2004
1CADASIL
12/2015
1Cerebellar Ataxia (Dysmetria)
03/2014
1Nervous System Diseases (Neurological Disorders)
12/2006
1Ataxia (Dyssynergia)
12/2006
1Dystonia (Limb Dystonia)
12/2006
1Epilepsy (Aura)
03/2004

Drug/Important Bio-Agent (IBA)

8voltage-dependent calcium channel (P-Q type)IBA
01/2017 - 03/2004
2Calcium Channels (Calcium Channel)IBA
01/2017 - 07/2010
1Notch3 ReceptorIBA
12/2015
1Biomarkers (Surrogate Marker)IBA
12/2015
1RNA (Ribonucleic Acid)IBA
03/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
09/2010
1Adenosine Triphosphatases (ATPase)IBA
05/2006
1Protein Isoforms (Isoforms)IBA
12/2004

Therapy/Procedure

1Therapeutics
12/2015